Peony is used for gout, osteoarthritis, fever, respiratory tract illnesses, and cough. Women use peony for menstrual cramps, polycystic ovary syndrome, premenstrual syndrome (PMS), and for starting menstruation. It is also used for viral hepatitis, livercirrhosis, upset stomach, muscle cramps, “hardening of the arteries” (atherosclerosis). Peony is also used for spasms, whooping cough (pertussis), epilepsy, nerve pain (neuralgia), migraineheadache, and chronic fatigue syndrome (CFS).


Use 2-3pcs flowers per 400ml of water. Heat water to 200 Degrees F and steep for 1-3 minutes. It's better to use glass cup to see the blooming of infusing.


People apply peony to the skin for healing cracked skin, especially cracks around the anus (anal fissures) that sometimes occur with hemorrhoids.


How does it work?
Peony might block chemicals produced by the body that can cause muscle cramps. It may also prevent blood clotting and act as an antioxidant.


Anti-oxidant activities:

Ethanol extract of the peony root (Paeonia Lactiflora Pall, Paeoniaceae)and its ingredients-gallic acid and methyl gallate showed protective effects against free radical generation, i.e. free radical scavenging effect against 1,1-diphenyl-2-picryl hydrazine, and lipid peroxidation.


Researchers also demonstrated the antioxidative activity of a few stilbene derivatives from seeds of Paeonia lactiflora wagainst the 2-deoxyribose degradation and rat liver microsomal lipid peroxidation. These compounds are stilbenes, trans-resveratrol, trans-resveratrol-4′-O-beta-D-glucopyranoside, trans-epsilon-viniferin, gnetin H, and suffruticosol A and B.


Korean researchers showed antioxidant activities of a few compounds of from peony (Paeonia suffruticosa). Alpha-benzoyloxypaeoniflorin and some other compounds exhibited moderately potent radical scavenging activity on DPPH radical.


Cut risks of certain cancers

Researchers showed the cytotoxic and antimutagenic effects of transresveratrol, trans-epsilon-viniferin, gnetin H, suffruticosols A and B, isolated from the seeds of peony (Paeonia lactiflora Pall) in a study of five different cancer lines. They showed cytotoxic activity in a dose-dependent manner, and especially did potent cytotoxic activity against C6 (mouse glioma)

cancer cell. Trans-Resveratrol showed significant cytotoxic activity against HepG2 (liver hepatoma) and HT-29 (colon) human cancer cell lines. While, trans-epsilon-viniferin and cis–viniferin, and gnetin H exhibited marked cytotoxic activity against Hela (cervicse) and MCF-7 (breast) human cancer cell lines.


Paeoniflorin, isolated from the methanol extract of peony (Paeonia lactiflora), showed a lowering effect on cholesterol level in the experimentally-induced hyperlipidemic rats. Paeoniflorin showed a significantly lowering effect of total cholesterol, LDL and triglyceride levels compared with the control group at the dose of 200 and 400 mg/kg, p.o. once a day for 4


Hypercholesterolaemia induced an increase of endothelial superoxide anion and endothelial dysfunction. Japanese researchers noticed that administration of the peony (paeonia lactiflora root) extract increased the endothelium-dependent relaxation and the activities of superoxide dismutase compared with high the cholesterol diet group significantly.


Immunological Modulation

Researchers from Kyoritsu College of Pharmacy,Japan, demonstrated the anti-complementary activities of an acidic polysaccharide isolated from the root of peony (Paeonia lactiflora PALLAS) – peonan PA. Peonan PA is composed of L-arabinose: D-galactose: D-galacturonic acid in the molar ratio of 2:1:10.




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